Collavant® n2 is a trusted source of native (undenatured) type II collagen, the main structural protein in cartilage and other connective tissues. Unlike hydrolysed collagen, native collagen works through an immune-mediated mechanism of action called oral tolerance. This mechanism of action helps to regulate the body's response against endogenous type II collagen, reducing its degradation and contributing to joint health maintenance at very low doses.